57% of Banking Executives Struggle with Data Silos, Blocking AI-Driven Personalization, CleverTap’s New Report Highlights JCN Newswire

57% of Banking Executives Struggle with Data Silos, Blocking AI-Driven Personalization, CleverTap’s New Report Highlights

SAN FRANCISCO, CA & MUMBAI, Nov 6, 2024 - (ACN Newswire via SeaPRwire.com) - CleverTap, the all-in-one engagement platform, today released its latest Market Research Report with insights into the global banking landscape, “Banking on AI: A Leader's Guide to Customer Engagement Excellence in Banking”. The report reveals that 57% of banking executives have yet to achieve a unified customer view, indicating significant challenges with data silos due to technological barriers and cost constraints. These data challenges are impacting banks’ ability to deliver personalized, seamless customer experiences in an era where AI-driven engagement is becoming essential.The research explores the transformative shift within the banking sector leveraging AI to address modern banking challenges, including the need for personalized and secure digital experiences amid rapid digital transformation. Through this study, CleverTap set out to identify where the AI opportunity lies for banks and introduced its strategic framework to help banks build excellence in customer engagement, along with highlighting key trends for Banks in customer engagement within the AI space, while understanding the challenges and opportunities faced by banking leaders. Furthermore, the company also assessed AI's role in enhancing customer experiences.The methodology included a survey of 50 senior executives in India’s banking sector, in-depth interviews for qualitative insights, and analysis of industry benchmarks and best practices. This research covered banks with a combined total asset size of about $3.03 trillion, spanning APAC, the Middle East, North America, LATAM, and the EU.Insights from the report reveal that 3 out of 4 banking executives may be missing out on critical opportunities to build customer loyalty and drive sustainable growth, as they focus heavily on short-term revenue targets. To effectively balance short-term metrics with long-term financial outcomes, banks need to harness advanced analytics that not only track current performance but also predict future customer behaviors.To assess the gaps and identify opportunities for the banking sectors in the age of AI, CleverTap has developed a framework that will serve as a foundation to improve customer experiences and drive long-term value. CleverTap’s Core Four Framework – encompassing Trust, Technology, Touchpoints, and Transactions – is designed to help banks transition from product-focused to customer-centric approaches, cultivating deeper relationships and delivering phy-gital experiences. The research covers the nuances for retail banks, neo-banks, and specialized banks, providing insights across the four core pillars.Key gaps identified basis of the framework include:Loyal customers generate 2.5x higher transaction value than others, and referred prospects are 3.5x more likely to onboard. However, 50% of banking executives do not effectively leverage their high-NPS (Net Promoter Score) customers57% of banking executives have yet to implement a unified customer view, suggesting issues with data silos. The primary obstacles to unification are technological challenges and associated costs41% of banking executives are not using real-time segmentation capabilities, limiting their ability to deliver timely and personalized communicationBanks using more than four channels in their engagement campaigns see a 53% improvement in conversions compared to those using fewer than four channels, yet only about 33% of banks have adopted this approachBanks can harness the power of the Core Four by implementing a comprehensive AI strategy, as detailed in CleverTap’s report Banking on AI: A Leader's Guide to Customer Engagement Excellence in Banking.This approach consists of three key stages:Operational Optimizers focus on using AI to enhance operational efficiency through the automation of routine tasks and improved workflow processesPersonalization & Experimentation Architects where AI is applied to improve orchestration while personalizing interactions and conducting experiments at scale to boost conversionStrategic Innovators showcase the use of AI for automating strategic decision-making and providing deeper insights for long-term planningCommenting on the report, Jacob Joseph, VP - Data Science, CleverTap said, “The banking sector has often played catch-up when it comes to tech innovations, but customer familiarity with digital solutions is making it clear that banks need to bridge this divide quickly. The banking sector often remains a 'follower' in tech adoption. This cautious stance means banks typically wait for proof of concept before fully embracing new technologies. Our latest report dives into how AI can bridge the current gaps in customer experience and operational efficiency, helping banks not only meet evolving customer expectations but exceed them. By deploying integrated, AI-powered solutions, banks can deliver the hyper-personalized experiences today’s customers expect, building lasting trust and loyalty. For banks aiming to stay competitive in a digital-first world, AI isn’t optional - it’s essential.”Looking ahead at the future of the banking sector with AI, CleverTap’s latest insights highlight six transformative AI outlooks that are poised to redefine customer engagement and operations:Customer engagement for banking is driven by innovations like synthetic data, which enhances analytics without compromising privacyBanks are also prioritizing emotional engagement, using AI to create immersive experiences and personalized gamification that fosters customer loyaltyModernizing MarTech through AI-powered ecosystems allows banks to integrate data and services seamlessly, enhancing customer experiencesA shift towards a customer-centric approach, leveraging AI for dynamic personalization, further strengthens relationships and retentionAdditionally, implementing responsible AI frameworks builds trust by ensuring transparency and complianceFinally, the collaboration with fintech firms through AI-powered open banking creates holistic financial ecosystems, offering a wider range of services and real-time insights to customers, thereby increasing trust and engagementFor more information and insights download the report here.About CleverTapCleverTap is the leading all-in-one customer engagement platform that helps brands unlock limitless customer lifetime value. CleverTap is trusted by over 2000 brands like Domino’s, Levis, Jio, Papa John’s, Zomato, Kotak Bank, Air Asia, Carousell, TD Bank, and Tesco to help build personalized experiences for all their customers. The platform is powered by TesseractDB™ – the world’s first purpose-built database for customer engagement, offering speed and cost efficiency at scale.Backed by top-tier investors such as Accel, Peak XV Partners, Tiger Global, CDPQ, and 360 One, the company is headquartered in San Francisco, with presence across Seattle, London, São Paulo, Bogota, Mexico, Amsterdam, Sofia, Dubai, Mumbai, Bangalore, Singapore, Vietnam, and Jakarta.For more information, visit clevertap.com or follow us on:LinkedIn: https://www.linkedin.com/company/clevertap/ X: https://twitter.com/CleverTap Forward-Looking StatementsSome of the statements in this press release may represent CleverTap's belief in connection with future events and may be forward-looking statements, or statements of future expectations based on currently available information. CleverTap cautions that such statements are naturally subject to risks and uncertainties that could result in the actual outcome being absolutely different from the results anticipated by the statements mentioned in the press release.Factors such as the development of general economic conditions affecting our business, future market conditions, our ability to maintain cost advantages, uncertainty with respect to earnings, corporate actions, client concentration, reduced demand, liability or damages in our service contracts, unusual catastrophic loss events, war, political instability, changes in government policies or laws, legal restrictions impacting our business, the impact of a pandemic, epidemic, any natural calamity and other factors that are naturally beyond our control, changes in the capital markets and other circumstances may cause the actual events or results to be materially different, from those anticipated by such statements. CleverTap does not make any representation or warranty, express or implied, as to the accuracy, completeness, or updated or revised status of such statements. Therefore, in no case whatsoever will CleverTap and its affiliate companies be liable to anyone for any decision made or action taken in conjunction.For more information:SONY SHETTYDirector, Communications, CleverTap+91 9820900036sony@clevertap.com ASHMIT CHAUDHARYAssociate Consultant, Archetype+91 8850752121ashmit.chaudhary@archetype.co Copyright 2024 JCN Newswire via SeaPRwire.com.
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Honda Unveils Electric Motorcycle Concept Models “EV Fun Concept” and “EV Urban Concept” at EICMA 2024 JCN Newswire

Honda Unveils Electric Motorcycle Concept Models “EV Fun Concept” and “EV Urban Concept” at EICMA 2024

Milan, Italy, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda has unveiled two electric motorcycle concept models, the “EV Fun Concept” and the “EV Urban Concept,” at EICMA 2024 in Milan, Italy (Press days: November 5-6, Public days: November 7-10).Honda world-premiered two concept models, the EV Fun Concept and the EV Urban Concept, at EICMA 2024.The EV Fun Concept is Honda’s first electric sports model and is scheduled to go on sale in 2025.The EV Urban Concept embodies Honda’s vision of urban mobility in the near future.Beyond 2025, Honda aims to increase the variety of its electric line-up with the aim of becoming the leading company for electric motorcycles.Honda aims to achieve carbon neutrality through all of its products and corporate activities by 2050, and in particular, achieve carbon neutrality for all of its motorcycle products in the 2040s. Toward this goal, Honda is working to electrify its motorcycles as the mainstay of its future environmental strategy.Honda has positioned 2024 as the first year for the global launch of its electric motorcycles and has begun full-scale entry into the electric motorcycle market, positioning the time up to 2026 as a period of market entry, and beyond 2026 as a period of business expansion.The EV Fun Concept is an electric motorcycle designed for fun use and was referred to at its “2023 Briefing on Honda Electric Motorcycle Business” meeting held on November 29, 2023. The EV Fun Concept is a naked sports model equivalent to a mid-sized internal combustion engine (ICE) motorcycle. It is Honda’s first electric sports model to be equipped with a fixed battery and is scheduled to be commercialized in 2025.The EV Urban Concept is an electric model that embodies Honda’s vision of urban electric mobility with its function-focused design, connected technologies, and in-house developed battery pack.With the addition of the new sports EV Fun Concept, and the EV Urban Concept-, Honda is making solid progress toward its plan to introduce 30 electric models globally by 2030.Honda will accelerate its efforts to develop a full lineup of electric motorcycles to meet the diversifying needs of customers and promote the development of a wide variety of electric vehicles. Through its efforts, Honda aims to expand its global market share and become the leading company also in the field of electric motorcycles.EV Fun ConceptThe EV Fun Concept is Honda’s first electric sports model and is being developed as a next-generation electric motorcycle that offers a new sensation of quiet riding and an emotional feeling unique to electric motorcycles.In addition to the high level of “riding, turning, and stopping” created by Honda’s long-developed motorcycle technologies, the new quiet, vibration-free ride that is only possible with electric power and the slim, easy-to-manage chassis package realized by its fixed battery will provide a new emotional experience that is very different to ICE motorcycles. Honda believes the new electric experience will enhance customers’ motorcycle lifestyles.The EV Fun Concept’s system and charging were developed by applying Honda’s know-how and technologies cultivated in its automobiles and power products. The battery is compatible with the CCS2* quick charger, the same standard as automobiles, and has been developed to optimize the balance between light weight and quick charging performance, as well as to provide a cruising range of over 100km or more, sufficient for city use.*CCS2: Combined Charging System Type 2, a specification for EV quick charging connectorsThe EV Urban Concept reconstructs from scratch Honda’s vision of what urban electric mobility should be. It embodies a vision of near-future mobility that cooperates and resonates with people and society through its essential and sophisticated styling, intuitive human-machine interface (HMI), and new experiences created by the fusion of software and hardware. Honda’s goal is to open up the freedom of mobility to as many customers as possible, and to expand the possibilities of mobility for each and every customer.Honda Motor Europe Limited, Honda’s UK subsidiary, has released details on the EV Fun Concept and EV Urban Concept on its website.Video site:URL: https://www.youtube.com/watch?v=v8hzcn4so7sAbout HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.
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Yoshimoto Kogyo and Mitsubishi Corporation have signed a business partnership agreement for co-creation of business using “laughter” JCN Newswire

Yoshimoto Kogyo and Mitsubishi Corporation have signed a business partnership agreement for co-creation of business using “laughter”

Yoshimoto Kogyo Holdings Co., Ltd. (hereinafter referred to as Yoshimoto Kogyo) and Mitsubishi Corporation have agreed to consider business co-creation, including solving consumers' health issues through “laughter”, overseas development of “comedy content”, and content production using digital transformation, and have concluded a business partnership agreement.With the advent of a super-aged society in Japan, there is a renewed focus on the health benefits of laughter, as people seek to prevent dementia and brain aging, and achieve well-being. Yoshimoto Kogyo and MC will work together to solve the health issues faced by consumers through laughter and health care. In addition, MC intends to widely promote Japan's excellent intangible assets as brands in the overseas markets and will jointly deliver Yoshimoto Kogyo's Japanese comedy content as an attractive intangible asset to the rest of the world. The companies will utilize MC's digital transformation expertise to capture and monitor consumer health data and to produce comedy content, aiming to co-create new added value through the combination of comedy and digital technology.Based on this agreement, Yoshimoto Kogyo will be responsible for the planning and production of content and collaborative goods that it has cultivated through its business to date, while MC will utilize its human resources and networks both in Japan and overseas, its business expertise in digital and health care, and its manufacturing and sales network for retail and miscellaneous goods. In addition, the two companies will aim to create new businesses through the exchange of human resources.Specifically, the companies will begin joint discussions on (1) new services based on solving health issues through laughter, (2) joint production and distribution of new content utilizing digital technology, (3) overseas development of comedy content, (4) regional revitalization utilizing the business platforms of both groups, (5) production and sales of merchandise, and (6) other new services.Through this initiative, Yoshimoto Kogyo and MC aim to provide “Smart Life,” a healthier and better lifestyle, to people around the world.About Yoshimoto Kogyo Holdings Co., Ltd.Head office: 11-6 Sennichimae, Namba, Chuo-ku, OsakaRepresentative: Akihiko Okamoto, President and Chief Executive OfficerEstablished: 1912Business description: Theater operation, talent agency, production and sales of video and other content, other businessesAbout Mitsubishi CorporationHead office: 3-1, Marunouchi 2-Chome, Chiyoda-ku, TokyoRepresentative: Katsuya Nakanishi, Representative Director, President and CEOEstablished: 1954Business description: The company develops diversified businesses in a wide range of industries through its eight groups: Environmental Energy, Materials Solution, Mineral Resources, Urban Development & Infrastructure, Mobility, Food Industry, S.L.C. (Smart-Life Creation), and Power SolutionInquiry RecipientMitsubishi CorporationTelephone: +81-3-3210-2171 Copyright 2024 JCN Newswire via SeaPRwire.com.
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Honda to Begin European Verification Test of Battery Sharing Service with GoCimo JCN Newswire

Honda to Begin European Verification Test of Battery Sharing Service with GoCimo

TOKYO, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda Motor Co., Ltd. (Honda) and GoCimo (formerly known as GoCiklo) (CEO: Mattias Tingvall), a Swedish start-up that operates rental and sharing service of electric motorcycles with swappable batteries, will together commence a battery sharing service verification test in Malmö, Sweden in February 2025 for a period of one year.The purpose of the test is to verify the acceptability of a battery sharing service in Europe, the suitability of a new battery swap station, and the business feasibility of the service.The test will consist of Honda Power Pack Exchanger e: (battery swap station), located at three locations in Malmö, to be used to exchange Honda Mobile Power Pack e: (batteries) for the EM1 e: (electric scooter commuter) sold by Honda in Europe. For this test, Honda will provide hardware and systems, including 30 pcs of EM1 e:, 60 pcs of Honda Mobile Power Pack e, and three Honda Power Pack Exchanger e:, as well as after-sales service.GoCimo was established in 2022 to address rising emissions and traffic congestion in the delivery and transportation industries, driven by the growth of the urban logistics market. So far, GoCimo has operated battery sharing services in two Swedish cities (Stockholm and Gothenburg). In this verification test, GoCimo will be responsible for the operation of the battery sharing service, customer acquisition and management, and securing locations for battery exchange stations.Honda and GoCimo will also evaluate the potential for a long-term partnership for the European market during the verification test.Honda has already launched battery sharing services in Japan, India, Indonesia, and Thailand. This verification test in Sweden will mark the fifth country for Honda’s battery sharing services.Beginning with this initiative with GoCimo, Honda aims to promote the electrification of motorcycles and the widespread use of swappable batteries in Europe by expanding battery sharing services using Honda products, mainly for business users, in major European cities, thus supporting the electrification of mobility and contributing to the realization of a low-carbon society.Daiki Mihara : Operating Executive, MCPP Elect Biz Dev Unit, Honda Motor Co., Ltd.“Honda is promoting the spread of electric motorcycles globally. The joint verification test of the battery sharing service with GoCimo will create a new business model for electric motorcycles in Europe, which will be commercialized and rolled out across the entire European region in the future to accelerate the spread of electric motorcycles and Honda Mobile Power Pack e:.”Mattias Tingvall : CEO GoCimo“GoCimo has successfully validated the business model for battery-sharing subscriptions for light vehicles in Europe. Our customers confirm that our service helps them transition to electric vehicles by lowering the investment hurdle, minimizing downtime due to charging, and improving safety during the charging process. This joint verification test with Honda allows us to further explore the market potential of battery-sharing services.”About HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.
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Honda Unveils World’s First and New V3 Engine with Electrical- Compressor at EICMA 2024 JCN Newswire

Honda Unveils World’s First and New V3 Engine with Electrical- Compressor at EICMA 2024

MILAN, Nov 6, 2024 - (JCN Newswire via SeaPRwire.com) - Honda unveiled the world’s first* V3 motorcycle engine with an electrical compressor, at EICMA 2024 (the Milan Motorcycle Shows; Press days: November 5-6, Public days: November 7-10) in Milan, Italy.The water-cooled 75-degree V3 engine is being newly developed for larger displacement motorcycles, and has been designed to be extremely slim and compact. It features the world’s first electrical compressor for motorcycles, which is able to control compression of the intake air irrespective of engine rpm, meaning that high-response torque can be delivered even from lower rpm. In addition, the electrical compressor allows a high degree of freedom of layout of all components in the limited space available on a motorcycle and efficient centralization of mass. It also does not require any form of intercooler. Honda’s motorcycle business aims to provide products that meet the needs of various customers by offering a wide range of products from commuters to FUN models. In addition, Honda is taking on the challenge of developing advanced technologies by adding electric motorcycles and other products to its product lineup to meet the diversifying needs of today’s customers.Honda sees the development of this V3 engine with an electrical compressor as a new challenge in the area of internal combustion engines, and its goal is to enable customers to further experience the joy of riding and owning a motorcycle. Honda plans to apply the new V3 engine to larger displacement models in the future, and will continue its development toward mass production.*Honda researchAbout HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.
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Victory and world title for TOYOTA GAZOO Racing JCN Newswire

Victory and world title for TOYOTA GAZOO Racing

Toyota City, Japan, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - TOYOTA GAZOO Racing completed a thrilling fightback to overcome challenges and retain its FIA World Endurance Championship (WEC) title when the 2024 season came to a dramatic conclusion in the 8 Hours of Bahrain.Starting from one-two on the grid, and knowing a win would secure the manufacturers’ title, each car led at different points, but the team entered the final stages of the race with only one car on track, down in 10th place after suffering setbacks.An incredible team effort and a dominant driving display saw Sébastien Buemi cut through the field to win the race in the #8 GR010 HYBRID he shares with Brendon Hartley and Ryo Hirakawa, securing the team’s sixth successive manufacturers’ World Championship, by six points from Porsche.The #7 GR010 HYBRID had victory in its sights when it led at half distance, but a fuel pump issue forced Mike Conway, Kamui Kobayashi and Nyck de Vries into retirement. That ended the slim drivers’ title hopes of Kamui and Nyck, who needed a win to have any chance.The chequered flag in Bahrain concluded a 2024 season which featured 72 hours of racing, at eight rounds on four continents over almost 10 months. TOYOTA GAZOO Racing’s season record stands at five podiums, including three wins, and two pole positions, earning 190 World Championship points. After an exciting year, TOYOTA GAZOO Racing congratulates new drivers’ World Champions Kévin Estre, Andre Lotterer and Laurens Vanthoor, and thanks all WEC competitors for their contribution to a memorable season.A dramatic and challenging race had started strongly for the team when Sébastien led away from pole. But after 18 minutes its hopes suffered a blow when Sébastien was hit from behind by a GT car and spun down to seventh. He recovered to fifth before Brendon took over late in the second hour.Brendon and Ryo then battled against tyre degradation on their stints but made a determined effort to keep the #8 in the top six and still in the hunt. The race turned on two safety car periods early in the second half of the race, which closed the gaps throughout the 18-strong Hypercar field.When racing resumed with just over an hour remaining, Sébastien was 10th but only 15secs from the lead, and he began an incredible fight back to revive the team’s World Championship dream. A heroic charge through the field saw him overtake several rivals to move into second after his final pit stop.With just over half an hour of the season remaining Sébastien completed a remarkable comeback drive by passing the #5 Porsche for the lead. He soon established a comfortable advantage and reached the chequered flag to win by 27.539secs for the #8 GR010 HYBRID’s second win of the season, and the team’s 10th in Bahrain.For much of the race, the #7 car had looked the most likely GR010 HYBRID to challenge for victory. Mike moved up from fourth at the end of the first lap to be in the top three when Kamui took the wheel for what would be a dramatic stint. As the sun set in the fourth hour, Kamui’s bold overtaking elevated him to second.However, the #7 was hit by a fuel pump issue which intermittently reduced performance. Drivers, engineers and mechanics looked for a solution and, initially, appeared to have succeeded when Kamui closed the gap and Nyck took the lead via a fast pit stop. But the trouble returned and the #7 slipped down the field.Considering the problem would require a lengthy repair, the team prioritised victory and the championship. It decided to retire the #7 with just over two hours to go, in order to allow its crew members to support the #8 car’s challenge, expressing their solidarity and ensuring today’s title triumph was a genuine team effort.Kamui Kobayashi (Team Principal and driver, car #7):“First of all, a big thank you for all the support we have had this season from all over the world. Winning the manufacturers’ World Championship is a great achievement and it’s the result of a huge team effort from everyone, including our Toyota colleagues and our partners, who are a big part of this success. This is the result everyone in the team wanted and they gave everything to achieve it, so thank you for all that work. Car #8 deserved the win today after an incredible race. Obviously on our car we had some issues and had to retire. We will analyse that and aim to come back even stronger next season.”Mike Conway (Driver, car #7):“It was obviously a disappointing outcome for our car. We were very strong at some points and looking good to win, then we ran into the issue which unfortunately took us out of the race. But at least car #8 won and that means we achieved our target of winning the manufacturers’ World Championship. I am very happy for the team and for Toyota, and I’m also pleased for car #8 to win the race with such a strong drive at the end. We’ll all enjoy this moment.”Nyck de Vries (Driver, car #7):“It’s great to end the season on a high for the team by winning the manufacturers’ World Championship with an amazing victory for car #8. Obviously, it’s bittersweet for our car to see our title rivals not score any points, considering we were in a winning position. Without the technical issue we had the chance to win both championships but that’s part of the game and we have to take it on the chin. Overall, I am just so happy for the team to get their reward today because they really deserve it after an eventful and challenging season.”Sébastien Buemi (Driver, car #8):“It’s crazy to think we won the race considering how it was going at some point. Against all the odds, with issues, penalties and bad luck it’s an amazing feeling for the team to win the World Championship. That was our target here and we’ve achieved it thanks to a brilliant effort from the team. When our car was down in 10th, we were going to the back of the Hypercar field during the pit stops and I thought we were done. But my team-mates did a good job hanging on with the old tyres and that meant I had a tyre advantage at the end. When it mattered today, we did a good job together and I am so pleased for the whole team.”Brendon Hartley (Driver, car #8):“I am so happy for everyone in the team and at Toyota. The race didn’t go as smoothly at the beginning as it could have done. We tried the medium tyres, but it didn’t work. Then at the end Séb did an unbelievable stint. He was the star; it was an incredible drive. Thanks to everyone in the team, at Toyota and all our partners. We really had to fight for this win and championship, so it means a lot. For our car to end the season with a victory is fantastic going into the winter break.”Ryo Hirakawa (Driver, car #8):“What a day. It was an up and down race, but we never gave up and we fought as one team. We started from pole, then got hit by a GT car but still tried our best and put everything behind Séb for a maximum push at the end. On the #8 car, we have had some difficulties this season, so I am happy to finally get a bit of luck. It’s fantastic to finish the season with a win and I am so grateful to the team, as well as to everyone at Toyota and all our partners, for their big efforts to win this manufacturers’ championship.”8 Hours of Bahrain – Result1st #8 TOYOTA GAZOO Racing 235 laps2nd #51 Ferrari AF Corse (Pier Guidi/Calado/Giovinazzi) +27.539secs3rd #5 Porsche Penske (Campbell/Christensen/Makowiecki) +29.177secs4th #93 Peugeot TotalEnergies (Jensen/Müller/Vergne) +36.799secs5th #35 Alpine Endurance Team (Chatin/Habsburg/Gounon) +37.404secs6th #15 BMW M Team WRT (Vanthoor/Marciello/Wittmann) +47.916secsDNF #7 TOYOTA GAZOO Racing Copyright 2024 JCN Newswire via SeaPRwire.com.
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Tokyo Stock Exchange and Fujitsu announce renewal of cash equity trading system ‘arrowhead4.0’ JCN Newswire

Tokyo Stock Exchange and Fujitsu announce renewal of cash equity trading system ‘arrowhead4.0’

TOKYO, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - Tokyo Stock Exchange, Inc. (TSE) and Fujitsu Limited today announced the successful renewal and operational launch of the TSE's cash equity trading system "arrowhead4.0." This renewal signifies the fourth generation of arrowhead, which originally commenced operations in January 2010.1. Key pointsIn this renewal, several measures have been implemented to enhance market convenience, including an introduction of the closing auction session, a new service that distributes market information by each order, and a bulk order cancellation function for users such as institutional investors. Additionally, to maximize trading opportunities for investors and other users, trading hours have been extended and resilience has been strengthened.(1) Improving Market Convenience- Introduction of the Closing Auction SessionConsidering the increasing importance of trading at close, and with the aim of further enhancing transparency in the formation of closing prices, this iteration of arrowhead introduces a closing auction session. This session provides a five-minute order acceptance period from 3:25 p.m. in the afternoon session, followed by a closing auction at 3:30 p.m. At the closing auction, even if orders do not match according to the previous rules, they can be executed at the upper or lower limits of the executable price range if certain conditions are met, thereby improving the opportunity for the formation of closing prices (Special Execution).- Market Information Service formed as a Market by OrderMarket by Order service, which distributes market information for each order, has been launched. This new service allows users to obtain more detailed market information for each order, in addition to the aggregated market information by price that has been available up to now.- Mass CancellationTo enhance convenience for users such as institutional investors, a function has been equipped that allows the cancellation of multiple orders in bulk on a user-by-user basis.(2) Maximizing Trading Opportunities- Extension of Trading HoursIn order to maximize trading opportunities for investors and improve the convenience of the market, the closing time of TSE has been extended by 30 minutes from 3:00 p.m. to 3:30 p.m.- Enhancement of ResilienceBy triplicating trading data in memory and operating multiple servers in parallel, it is now possible to switch servers in seconds and to ensure data integrity in the event of system failures, thereby realizing safe and secure system operation. In preparation for system failures, it continues to make improvements to ensure the continuation of trading. It will also be able to ensure trading opportunities through efforts to recover the system more quickly and smoothly than ever before.2. The Highly Reliable Technology and Support behind “arrowhead4.0”System reliability and processing performance have been improved by combining Fujitsu’s latest products, including reliable and high-performance servers, and middleware incorporating new high-speed technologies, with the know-how and technical capabilities of engineers who have built systems over many years.Based on the high-quality system development process that has been built and improved through arrowhead project in the past, the following efforts have been made to further enhance reliability and stability and improve resilience.(1) Introduction of Resilience Improvement FunctionsWith Fujitsu Software Primesoft Server, ultra high-speed in-memory data management software that combines high reliability and scalability, transaction data is placed in memory to achieve high response performance from ultra high-speed data access at the microsecond (one millionth of a second) level and throughput performance is achieved by placing transaction information in memory.Furthermore, product improvements have been made to shorten failure recovery time with system reboots. In addition, a monitoring dashboard was constructed to visualize the normality of the services provided by arrowhead4.0.(2) Improvement of System Performance and ToleranceBy upgrading the infrastructure to 462 PRIMERGY RX2540 M6 (1) servers, the latest high-performance and high-reliability x86 servers from the Fujitsu Group, system performance, including capacity and throughput, has been improved, and tolerance has been enhanced.(3) Promotion of “loosely-coupled” systemsThe system log data storage for business analysis was separated from the trading core function, and built on a cloud computing platform provided by Japan Exchange Group, Inc. By loosely coupling some of the functions of data analysis and trading on the system, the reliability of market operations was improved. In addition, more flexible market data analysis is now possible.(4) Advanced Failure ResponseTSE and Fujitsu have built a unified team to respond to system failures. In the case of a system failure, the team will work quickly to identify the cause of the failure and the scope of the impact.3. About the FutureTSE and Fujitsu will continue to further develop the market by responding to changes in the market environment and diversifying investor needs, further enhancing the convenience of market users and the international competitiveness and resilience of the Tokyo market, as well as realizing safe and secure trading on the market.TrademarksAll company or product names mentioned herein are registered trademarks of their companies.[1]“PRIMERGY RX2540 M6” :Fujitsu Group's x86 servers. The PRIMERGY brand was transferred to Fsas Technologies Inc. in April 2024.About Tokyo Stock Exchange, Inc. (TSE)Tokyo Stock Exchange is licensed as a financial instruments exchange under the Financial Instruments and Exchange Act and operates financial instruments markets.The market capitalization of companies listed on the Tokyo Stock Exchange is the third largest in the world and the largest in Asia, and we have established our position as the central market in Japanese securities.Tokyo Stock Exchange is a wholly owned subsidiary of Japan Exchange Group, Inc. (Code: 8697).About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsTokyo Stock Exchange, Inc. IT Development Department Trading SystemTEL:+81-3-3666-0141 (representative)Fujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.
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Mitsubishi Heavy Industries Continues Order Intake, Revenue, and Profit Growth in Strong First Half, Raises Full-Year Order Intake Guidance JCN Newswire

Mitsubishi Heavy Industries Continues Order Intake, Revenue, and Profit Growth in Strong First Half, Raises Full-Year Order Intake Guidance

- Order intake grew YoY in Energy Systems, Plants & Infrastructure Systems, and Logistics, Thermal & Drive Systems segments due to contributions from GTCC and Aero Engines in Energy Systems and Metals Machinery in Plants & Infrastructure Systems.- Revenue increased YoY in Energy Systems, Plants & Infrastructure Systems, and Aircraft, Defense & Space segments. Revenue growth was especially large in Aircraft & Missile Systems within Defense & Space.- Business profit showed strong YoY growth in Energy Systems, Plants & Infrastructure Systems, and Aircraft, Defense & Space segments due to positive impact of revenue increases, margin improvements, and yen depreciation.- Increased full-year order intake guidance mainly due to continued strong demand in Energy Systems segment.TOKYO, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI, TSE Code: 7011) announced that order intake rose 7.9% year-on-year to ¥3,383.5 billion in the half year ended September 30, 2024. Revenue rose 11.1% to ¥2,298.1 billion year-on-year, resulting in profit from business activities (business profit) of ¥188.4 billion, an 86.7% increase over the previous fiscal year, which represents a profit margin of 8.2%. Profit attributable to owners of parent (net income) was ¥107.1 billion, an increase of 16.5% year-on-year, with a profit margin of 4.7%. EBITDA was ¥266.2 billion, a 57.7% increase over 1H FY2023, with an EBITDA margin of 11.6%, up 3.4 percentage points year-on-year.(billion yen, except where otherwise stated)1H FY2024 Financial Results1H FY20231H FY2024YoYYoY%Order Intake3,137.03,383.5+246.4+7.9%Revenue2,069.22,298.1+228.8+11.1%Profit from Business ActivitiesProfit Margin100.94.9%188.48.2%+87.4+3.3 pts+86.7%-Profit Attributable to Owners of ParentProfit Margin91.94.4%107.14.7%+15.1+0.3 pts+16.5%-EBITDAEBITDA Margin168.98.2%266.211.6%+97.3+3.4 pts+57.7%-FCF-181.2-85.7+95.5-(billion yen, except where otherwise stated)1H FY2024 Financial Results by SegmentOrder IntakeRevenueBusiness Profit1HFY2024YoY1HFY2024YoY1HFY2024YoYEnergy Systems (Energy)1,306.7+225.6832.1+71.2103.2+61.5Plants & Infrastructure Systems (P&I)599.4+176.6379.1+12.128.1+12.0Logistics, Thermal & Drive Systems (LT&D)657.6+7.6632.8-0.526.9-9.7Aircraft, Defense & Space (ADS)802.1-197.2431.7+112.744.0+16.5Others, Corporate & Eliminations (OC&E)17.5+33.822.2+33.2-13.8+7.1Total3,383.5+246.42,298.1+228.8188.4+87.4In Energy, order intake increased by ¥225.6 billion YoY as Gas Turbine Combined Cycle (GTCC) and Aero Engines continued to see strong demand. Contracts for nine large frame gas turbine units were concluded in the first half, with the largest YoY growth seen in the Americas. Revenue increased by ¥71.2 billion YoY mainly from large volume in Aero Engines and steady project execution in GTCC and Nuclear Power. Margin improvements in GTCC and Steam Power, together with higher revenue and a rebound from 1H FY2023 one-time expenses in Aero Engines, as well as stable performance in Nuclear Power served to increase segment business profit by ¥61.5 billion YoY.In P&I, order intake was up ¥176.6 billion YoY due to strength in Metals Machinery, Machinery Systems, and Waste-to-Energy Systems. Revenue grew by ¥12.1 billion as Metals Machinery continued to work through its extensive backlog. Margin improvements in Engineering and Machinery Systems, combined with increased revenue in Metals Machinery helped to raise segment business profit by ¥12.0 billion YoY.In LT&D, revenue was down ¥0.5 billion YoY due to fewer unit deliveries in Logistics Systems. This issue, combined with additional costs caused by supply chain disruption in Turbochargers resulted in a ¥9.7 billion decline in segment business profit.In ADS, order intake decreased by ¥197.2 billion YoY in response to extremely large orders volume in 1H FY2023 in Defense & Space. Revenue was up ¥112.7 billion YoY mainly due to growth in Aircraft & Missile Systems in Defense & Space. Higher unit deliveries and positive impact from the depreciation of the yen in Commercial Aircraft also served to increase revenue. The factors affecting revenue also served to raise segment business profit by ¥16.5 billion YoY. FY2024 Earnings ForecastMHI revised its guidance for the period ending March 31, 2025, increasing the target for order intake by ¥200 billion over the previous announcement made August 6, 2024. This was in response to steady progress mainly in Energy. Totals for all other financial indicators remained unchanged, while business profit targets for Energy, P&I, and LT&D were updated.(billion yen, except where otherwise stated)FY2024 Earnings ForecastFY2023ActualFY2024Forecast(Previous)FY2024Forecast(Revised)Revised vs.PreviousOrder Intake6,684.05,800.06,000.0+200.0Revenue4,657.14,900.04,900.0-Profit from Business ActivitiesProfit Margin282.56.1%350.07.1%350.07.1%--Profit Attributable to Owners of ParentProfit Margin222.04.8%230.04.7%230.04.7%--ROE11.1%10%10%-EBITDAEBITDA Margin432.69.3%500.010.2%500.010.2%--FCF200.1-100.0-100.0-Dividends20 yen(Note)22 yen22 yen-FY2023 Actual dividends (¥200/share) shown here adjusted retroactively to 1/10 of original value to reflect the 10-for-1 stock split effective April 1, 2024. (billion yen, except where otherwise stated)FY2024 EarningsForecast by SegmentOrder IntakeRevenueBusiness ProfitPreviousRevisedPreviousRevisedPreviousRevisedEnergy1,850.02,000.01,750.01,750.0170.0180.0P&I900.0900.0800.0800.030.040.0LT&D1,350.01,350.01,350.01,350.080.060.0ADS1,700.01,700.0950.0950.080.080.0OC&E0.050.050.050.0-10.0-10.0Total5,800.06,000.04,900.04,900.0350.0350.0CFO Message"In the first half of this fiscal year, MHI continued the strong growth trend started in the first quarter, with order intake, revenue, business profit, and net income all up year-on-year," Hisato Kozawa, MHI Chief Financial Officer commented. Kozawa continued, "In terms of order intake, GTCC and Aero Engines in Energy, and Metals Machinery in P&I were stand-outs, enabling YoY orders growth despite the extremely high level achieved during the same period last year in Defense & Space. Revenue was up mainly in Energy and ADS as these segments steadily executed on their large order backlogs. These revenue increases, combined with margin improvements and depreciation of the yen helped us to greatly increase progress toward our business profit guidance of ¥350 billion.""Based on our results through September of this year, especially in Energy, we have increased our full-year order intake guidance by ¥200 billion," Kozawa went on. "We have also updated the business profit forecast for three of our segments in order to reflect the faster progress seen in Energy and P&I, and the slightly lagging performance in LT&D. All other targets have been restated. Looking forward to the remaining two quarters, we aim to outperform current business profit guidance by continuing the strong trends from the first half while effectively controlling one-time expenses."Attachment 1: 1H FY2024 Financial ResultsFinancial Results (444 KB)Attachment 2: Presentation Materials of Financial ResultsPresentation Materials (888 KB)Downloadable PDF of this press releasePress Release (168 KB) Note regarding forward looking statements:Forecasts regarding future performance outlined in these materials are based on judgments made in accordance with information available at the time they were prepared. As such, these projections include risk and uncertainty. Investors are recommended not to depend solely on these projections when making investment decisions. Actual results may vary significantly from these projections due to a number of factors, including, but not limited to, economic trends affecting the Company's operating environment, fluctuations in the value of the Japanese yen to the U.S. dollar and other foreign currencies, and trends in Japan's stock markets. The results projected here should not be construed in any way as a guarantee by the Company.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.
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Eisai’s Corporate Venture Capital Subsidiary, Eisai Innovation, Inc., Selected for AMED’s ‘Strengthening Program for Pharmaceutical Startup Ecosystem” JCN Newswire

Eisai’s Corporate Venture Capital Subsidiary, Eisai Innovation, Inc., Selected for AMED’s ‘Strengthening Program for Pharmaceutical Startup Ecosystem”

TOKYO, Nov 5, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Eisai’s corporate venture capital subsidiary, Eisai Innovation, Inc. announced today that Eisai Innovation,Inc. has been selected as a registered venture capital (Registered VC) of the Strengthening Program for Pharmaceutical Startup Ecosystem implemented by the Japan Agency for Medical Research and Development (AMED).To address the shortage of large-scale funding necessary for new drug development, this program provides subsidies to pharmaceutical startups for development and commercialization. This support is contingent upon startups securing funding from AMED-registered venture capital firms, which specialize in drug development and offer hands-on business management and commercialization support.The Eisai global network of affiliated companies (the “Eisai Group”) launched its venture investment business in May 2019, aiming to support the acceleration of drug discovery innovation and the establishment of an ecosystem platform in areas includingdementia. This involves supporting the discovery of innovative technologies and services by supporting venture businesses with such capabilities and exploring possible future collaborations with these businesses. Eisai Innovation, Inc. was established in theU.S. in August 2019 as Eisai’s corporate venture capital subsidiary. It identifies opportunities for the Eisai Group to invest in venture businesses that align with Eisai’s goal of contributing to patients, focusing on cutting-edge drug discovery platforms, andnew modalities, as well as leading biotechnology in focus areas of neurology, oncology, and global health. The company also supports investment in drug discovery technologies in other areas, where significant future innovations are anticipated. As anAMED-registered VC, Eisai Innovation, Inc. aims to further contribute to strengthening the drug discovery venture ecosystem in Japan.Eisai and Eisai Innovation, Inc. are committed to utilizing their participation in the Strengthening Program for PharmaceuticalStartup Ecosystem to accelerate flexible support of academia, drug discovery ventures, and IT ventures, to create innovative new medicines targeting diseases with high unmet medical needs., Eisai aims to effectively achieve social good in the form of relievinganxiety over health and reducing health disparities by creating solutions through an ecosystem in collaboration with other industries.*Please refer to following web page for Eisai’s venture investment businesswww.eisai.com/innovation/cvc/index.html https://www.eisaiinnovation.com/MEDIA CONTACTSEisai Co., Ltd.Public Relations Department TEL : +81 (0)3-3817-5120Eisai Innovation, Inc. https://www.eisaiinnovation.com/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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Asahi Kasei and Honda Sign Shareholders’ Agreement to Convert Existing Asahi Kasei Subsidiary into Joint Venture for Production of Lithium-ion Battery Separators in Canada JCN Newswire

Asahi Kasei and Honda Sign Shareholders’ Agreement to Convert Existing Asahi Kasei Subsidiary into Joint Venture for Production of Lithium-ion Battery Separators in Canada

TOKYO, Nov 4, 2024 - (JCN Newswire via SeaPRwire.com) - Asahi Kasei Corporation (Asahi Kasei) and Honda Motor Co., Ltd. (Honda) announced today that the two companies have signed a shareholders’ agreement to convert an existing Asahi Kasei subsidiary in Canada into a joint venture company. This agreement was reached as a result of continued discussions on collaboration for the production of lithium-ion battery separators in Canada based on the basic agreement the two companies announced on April 25, 2024.Configuration for separator production in North AmericaThe two companies plan to convert E-Materials Canada Corporation (E-Materials), a wholly owned subsidiary of an Asahi Kasei subsidiary in Canada, into a joint venture between Asahi Kasei and Honda to be renamed Asahi Kasei Honda Battery Separator Corporation (tentative name). This will be based on Honda Canada Inc., a Honda subsidiary in Canada, acquiring a 25% stake by subscribing to new shares to be issued by E-Materials through a third-party allotment. Honda will invest a total of approximately C$417 million (approximately US$300 million) combining the subscription of new shares and other investment in this joint venture. The two companies will combine each other’s strengths, such as high value-added material technologies and electrification technologies, to produce high-quality separators to be utilized for lithium-ion batteries that will accelerate the realization of high-performance electrified vehicles.The two companies plan to establish and start the operation of the joint venture company in early 2025, subject to obtaining permits and approvals from relevant authorities.Comments by Ryu Taniguchi, President & Representative Director, Asahi Kasei Battery Separator Corp.“At the beginning of October we launched Asahi Kasei Battery Separator as a new company for the Hipore™ separator business to achieve more nimble management for this essential component of lithium-ion batteries. I am confident that we can continue to leverage the technology and experience gained with Hipore™ as well as our global network and diverse personnel to realize innovations in batteries for the future of energy storage. As Honda strives toward the goal of carbon neutrality by 2050, it is building a comprehensive electric vehicle value chain in Canada, where it has a history of conducting business for more than 50 years. Our partnership will not only establish stable supply of separators in North America, together we will enhance battery performance and durability to advance the energy transition through electric vehicles, making an important contribution to sustainability.”About the joint venture company (tentative)- Company name:Asahi Kasei Honda Battery Separator Corporation (tentative)- Location:Port Colborne, Ontario, Canada- Capital:Approximately C$240 million- Investment ratio:75% Asahi Kasei Battery Separator Canada Corporation25% Honda Canada Inc.Outline of the investment by the joint venture company (tentative)Plant overview:Integrated plant for the base film manufacturing and coating of Hipore™ lithium-ion battery separatorTotal investment amount:180 billion yen(with assumed exchange rate of 1 USD=145 yen)Production capacity:Approximately 700 million m2 per year (as coated film)Start of operationsCommercial start-up scheduled in 2027About HondaSince its foundation, Honda has been committed to "creating a society that is useful to people" by utilizing its technologies and ideas. We also focus on environmental responsiveness and traffic safety, and continue to take on the challenge of realizing a sustainable future. For more information, visit https://global.honda/en/.Head Office Contact Information: 2-1-1, Minami-Aoyama, Minato-ku, Tokyo 107-8556, JapanTel: +81-(0)3-3423-1111 (main) Copyright 2024 JCN Newswire via SeaPRwire.com.
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Joby Aviation and Toyota Accelerate Efforts to Realize Air Mobility JCN Newswire

Joby Aviation and Toyota Accelerate Efforts to Realize Air Mobility

Susono, JAPAN and Santa Cruz, California, Nov 4, 2024 - (JCN Newswire via SeaPRwire.com) - Toyota Motor Corporation (Toyota) and Joby Aviation (Joby) came together at Toyota's Higashi-Fuji Technical Center (Shizuoka, Japan) to assert their collective passion and ambition for air mobility in a gathering that included executives from both companies, Akio Toyoda, the chairman of the Toyota Group, and Joby CEO and founder, JoeBen Bevirt, along with Joby's air taxi, an electric vertical takeoff and landing aircraft (eVTOL*).Since its founding, Toyota has been working to realize a society in which everyone can move freely. About 100 years ago, in 1925, Sakichi Toyoda, founder of the Toyota Group, offered a prize to encourage the development of a storage battery that could provide enough performance "to fly an airplane across the Pacific Ocean." Since then, Toyota has continued to focus on the challenge of air mobility through the generations. Toyota Motor Corporation founder Kiichiro Toyoda also expressed a strong interest in the aircraft business, making prototypes of helicopters and aircraft components. After World War II, among other developments, Dr. Shoichiro Toyoda was involved in the joint development of the world's first electronically controlled aero piston engine with an American company at Toyota's Higashi Fuji Technical Center, which could be described as the birthplace of Toyota's development of air mobility. Today, Sakichi's dream carries on, with batteries seen as a viable source of power for eVTOL.As Toyota transforms into a mobility company, it has been able to work with other great companies like Joby to find new and exciting opportunities. Joby's CEO, JoeBen Bevirt, is driven by his passion and dreams that "look forward to a world where our environmental footprint is smaller, a world where we're able to spend more time with the people and places that matter most to us, without having to worry about traffic jams." Akio Toyoda, chairman of the Toyota Group, has ambitions to bring the freedom of mobility to all people. The two leaders met and began a journey together. The culmination of the efforts of both companies over the last seven years, in which Joby's dream and passion for air mobility as a startup met Toyota's expertise in production processes and technology development, led to Joby's first air taxi exhibition flight overseas in Japan.JoeBen Bevirt, Founder and CEO of Joby (left), Akio Toyoda, Chairman of Toyota Motor Corporation (right)"This is a moment we have been looking forward to for a long time and marks a significant milestone on our journey towards making clean air travel an everyday reality," said JoeBen Bevirt, Founder and CEO of Joby. "We share Toyota's vision for the future of air travel and are honored to have had the opportunity to present a glimpse of that future through our exhibition flight in Japan."Link to full speech script"Air mobility has the potential to change our `sense of distance and time,' and open a future with the new option of air mobility that will further enrich the lives of many people," said Hiroki Nakajima, member of the board and executive vice president of Toyota Motor Corporation. "Toyota is committed to deepening our collaboration with Joby and we will continue to work together to realize our shared dreams."Link to full speech scriptToyota is committed to building on its mobility businesses to deliver mobility for all, and to bring smiles to people's faces. Together, Toyota and Joby will work to realize a future that offers more freedom and prosperity to all.About electric Vertical Take Off and Landing (eVTOL)An eVTOL is a type of aircraft designed for short-range, high-frequency operations suitable for the on-demand air taxi market, which is expected to be utilized by commuters, business travelers, and tourists in urban areas. Combining elements from helicopters, drones, and small aircraft, eVTOLs aim to excel in reliability, environmental performance (zero operating emissions), quiet operation, operational and maintenance costs, enhanced safety features, and more.*Electric Vertical Take-Off and Landing eVTOLAbout Toyota Toyota strives to be a strong corporate citizen, engaging with and earning the trust of its stakeholders, and to contribute to the creation of a prosperous society through all its business operations.Our corporate principles form the basis of our initiatives, reflect values that enable action, and drive our mindset.For the latest Toyota-related news and information:https://tinyurl.com/ToyotaPressReleasenewsroom@global.toyota Copyright 2024 JCN Newswire via SeaPRwire.com.
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Eisai Completes Rolling Submission to US FDA for LEQEMBI(R) (lecanemab-irmb) Biologics License Application for Subcutaneous Maintenance Dosing for the Treatment of Early Alzheimer’s Disease Under the Fast Track Status JCN Newswire

Eisai Completes Rolling Submission to US FDA for LEQEMBI(R) (lecanemab-irmb) Biologics License Application for Subcutaneous Maintenance Dosing for the Treatment of Early Alzheimer’s Disease Under the Fast Track Status

TOKYO and CAMBRIDGE, Mass., Nov 1, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that Eisai has completed the rolling submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for lecanemab-irmb (U.S. brand name: LEQEMBI®) subcutaneous autoinjector for weekly maintenance dosing after it was granted Fast Track designation by the FDA. LEQEMBI is indicated for the treatment of Alzheimer’s disease (AD) in patients with Mild Cognitive Impairment (MCI) or mild dementia stage of disease (collectively referred to as early AD). If the FDA accepts the BLA, the Prescription Drug User Fee Act (PDUFA) action date (target date for completion of examination) will be set.The BLA is based on data from the Clarity AD (Study 301) open-label extension (OLE) and modeling of observed data. If approved by the FDA, the LEQEMBI autoinjector could be used to administer LEQEMBI at home or at medical facilities, and the injection process is expected on average to take about 15 seconds. As part of the subcutaneous autoinjector 360 mg weekly maintenance regimen under review, patients who have completed the biweekly intravenous (IV) initiation phase would receive weekly doses that maintain effective drug concentrations to sustain the clearance of highly toxic protofibrils* which can continue to cause neuronal injury even after the amyloid-beta (Aβ) plaque has been cleared from the brain.AD is an ongoing neurotoxic process that begins before and continues after plaque deposition. Data suggest that early and continuing treatment may prolong the benefit of therapy even after plaque is cleared from the brain. This SC autoinjector is expected to be easier for patients and their care partners to use and may reduce the need for hospital or infusion site visits and nursing care compared to IV administration. In addition to potentially maintaining the clinical and biomarker benefits, subcutaneous maintenance dosing may be more convenient for patients and their care partners to continue the treatment.LEQEMBI is approved in the U.S., Japan, China, South Korea, Hong Kong, Israel, UAE and Great Britain. Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU). The US FDA accepted Eisai’s Supplemental Biologics License Application (sBLA) for monthly LEQEMBI IV maintenance dosing in June 2024 and set a PDUFA action date for January 25, 2025.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority.* Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.1 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.2INDICATIONLEQEMBI® [(lecanemab-irmb) 100 mg/mL injection for intravenous use] is indicated for the treatment of Alzheimer’s disease (AD). Treatment with LEQEMBI should be initiated in patients with mild cognitive impairment (MCI) or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.For the full press release, visit https://www.eisai.com/news/2024/news202482.html. About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved in the U.S.,3 Japan,4 China,5 South Korea,6 Hong Kong,7 Israel,8 the United Arab Emirates9 and Great Britain.10 Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU).LEQEMBI’s approvals in these countries was based on Phase 3 data from Eisai’s, global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB). In the Clarity AD clinical trial, treatment with lecanemab reduced clinical decline on CDR-SB by 27% at 18 months compared to placebo.11,12 The mean CDR-SB score at baseline was approximately 3.2 in both groups. The adjusted least-squares mean change from baseline at 18 months was 1.21 with lecanemab and 1.66 with placebo (difference, −0.45; 95% confidence interval [CI], −0.67 to −0.23; P
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Mazda Launches Redesigned Corporate Website JCN Newswire

Mazda Launches Redesigned Corporate Website

HIROSHIMA, Japan, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation today launched a redesigned corporate website. Amid growing awareness and interest in sustainability, the company redesigned its website to provide stakeholders visiting the corporate website with more timely and user-friendly access to financial and non-financial data as well as information about initiatives set to enhance both corporate and social value.Within the corporate website, it also set up MAZDA MIRAI BASE, a new owned-media platform filled with videos and photos, to share stories about Mazda’s work to build a better future.Mazda Motor Corporation Website URL:Japanese - www.mazda.com/ja/English - www.mazda.com/en/MAZDA MIRAI BASE URL:Japanese - www.mazda.com/ja/mazda-mirai-base/English - www.mazda.com/en/mazda-mirai-base/Key ImprovementsMazda’s website that presents the company’s worldview more clearly offering enhanced usabilityTo help our stakeholders quickly find information they need and access a broader range of corporate data, Mazda redesigned its website structure and reorganized the information posted. In addition, the content was optimized to convey Mazda’s corporate philosophy, established last year, and value creation approach, arranging these in a restructured corporate website that articulates our worldview seeking to create a vibrant future.New MAZDA MIRAI BASE platformThis new owned-media platform MAZDA MIRAI BASE has been created to share Mazda’s aspirations and initiatives for realizing its corporate philosophy and 2030 Vision. Working from the concept of a “media platform that connects with partners to create an exciting future,” MAZDA MIRAI BASE distributes articles, video and photos to tell stories about ”creating the joy of living” found in manufacturing safe and reliable automobiles, manufacturing sustainably, and creating moving experiences.Mazda will continue to pursue the ‘Joy of Driving’ under its core value “Human Centric,” and aim to deliver the ‘Joy of Living’ by creating moving experiences in customers' daily lives.Reference:Mazda’s Corporate Philosophy- Japanese https://www.mazda.com/ja/about/philosophy/- English https://www.mazda.com/en/about/philosophy/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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NTT and Toyota Motor Corporation agree to joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents JCN Newswire

NTT and Toyota Motor Corporation agree to joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents

Toyota City, Japan, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Today, Toyota Motor Corporation (hereafter, Toyota) and Nippon Telegraph and Telephone Corporation (hereafter, NTT) have agreed to a joint initiative in the field of mobility and AI/telecommunications with the aim of realizing a society with zero traffic accidents.Through their previous collaborations, the two companies have confirmed that they share common values, such as contributing to society through technological and industrial development, a people-centered approach, and global contributions that start in Japan. This time, they will further deepen their collaboration with the aim of achieving a "society with zero traffic accidents" as the first step towards realizing a prosperous mobility society where safety and freedom are in harmony.In order to achieve a society with zero traffic accidents, it is necessary to take an infrastructure-cooperative approach that constantly connects people, mobility and infrastructure, in addition to the advancement of driving support technology based on data-driven technology in cars and the development of future automated driving technology.To achieve both of these things, Toyota is developing Software Defined Vehicles (SDV) with safety and security as the top priority. Alongside the evolution of SDV, it will become more important to build infrastructure such as a high-speed, high-quality communication infrastructure, an AI infrastructure that can collect and intelligently process vast amounts of information, and a computing infrastructure.In this collaboration, NTT, whose strengths lie in the telecommunications, and Toyota will jointly build a "Mobility AI Platform" that combines a seamless communications infrastructure with AI and computing platforms that can intelligently process large amounts of data. By doing so, they aim to connect people, mobility, and infrastructure to realize a safe, secure, and sustainable mobility society with no traffic accidents.Details of the joint initiativeWe will jointly develop and operate the "Mobility AI Platform" and use it in our efforts(1) to achieve a society with zero traffic accidents. The Mobility AI Platform is made up of multiple elements(2).The Mobility AI Platform aims to standardize the mobility field, and we envision that it will be used not only by the two companies, but also by a wide range of industry, government, and academic partners who share the goal of realizing a society with zero traffic accidents.Through this initiative, the two companies expect to invest a total of 500 billion yen by 2030. Starting in 2025, they will begin development of the Mobility AI Platform, and from around 2028 under the three-pronged infrastructure, they will begin social implementation and collaboration with various partners, aiming for widespread adoption from 2030 onwards.(1) Main initiatives aimed at achieving a society with zero traffic accidents- Three-pronged infrastructure collaboration" to prevent collisions at blind intersections, etc.- Development of advanced driving support/future automated driving systems" that are data-driven, with AI learning on its own based on large amounts of driving data(2) Elements that make up the mobility AI platform1. Distributed computing platform (data center)Computing resources (data centers) for analyzing and processing vast amounts of data using AI are installed in distributed locations, utilizing IOWN's optical communication technology. By locating them in areas rich in renewable energy, we can achieve local production for local consumption of electricity, and by achieving high power efficiency in the coordination and processing of distributed computing resources and AI, we can promote the greening of the vast amounts of electricity needed for data analysis and processing.2. Intelligent communication infrastructureA system is being built to coordinate human mobility infrastructure through seamless communication that is suitable for various traffic environments and conditions in urban areas, rural areas, and suburbs. In addition to being highly reliable, it also achieves low-latency communication for large volumes of data.3. AI infrastructureA platform that achieves mobility AI that learns and infers from various data from human mobility infrastructure, based on a "distributed computing infrastructure (data center)" and "intelligent communication infrastructure". Copyright 2024 JCN Newswire via SeaPRwire.com.
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All-New Triton Wins Golden Award at VMARK Vietnam Design Awards 2024 JCN Newswire

All-New Triton Wins Golden Award at VMARK Vietnam Design Awards 2024

TOKYO, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Motors Corporation (hereafter, Mitsubishi Motors) announced that the all-new Triton has been selected as a golden award winner at the VMARK Vietnam Design Awards 2024 in the Best Transportation Design category. This marks the second time that Mitsubishi Motors has won the award, after the Xforce topped the same category in 2023.Established in 2018, the VMARK Vietnam Design Awards is organized by the VDAS Design Association based in Ho Chi Minh City. This year, a jury of 42 internationally renowned design practitioners evaluated design projects from Vietnam and around the world, and each entry was evaluated against the five criteria of innovativeness, eco-friendliness, identity, functionality, and community. The most outstanding designs received the golden award, and this year, 19 projects were selected as gold award winners out of a total of 700 entries.The Triton is Mitsubishi Motors' one-ton pickup truck that traces its roots back to the Forte originally released in 1978. In the 45 years since, this global strategic vehicle from Mitsubishi Motors has sold a cumulative total of approximately 5.7 million units in approximately 150 countries spanning five generations of models. Developed under the product concept of "Power for Adventure," the all-new Triton features a complete overhaul of everything from the interior and exterior design to the chassis, ladder frame and engine, and more. It was first launched in Thailand – where its production site is located – in July 2023 and introduced in Japan in February 2024. The all-new Triton is being rolled out sequentially in 100 countries worldwide.In attending the VMARK Vietnam Design Award 2024 ceremony, Kazuhiro Watanabe, Division General Manager of Sales & Marketing Division, Mitsubishi Motors Vietnam Co., Ltd., commented: “This award is a testament to our 30-year journey of 'Drive ahead together for everyday Adventure' in Vietnam. The all-new Triton embodies this commitment by delivering exceptional quality, innovation, and a driving experience that resonates with the adventurous spirit of the Vietnamese people.”Norihiko Yoshimine, Product Design Director, Mitsubishi Motors, who designed the Triton, cheerfully commented, “The Triton expresses the majestic aura that is distinctively Mitsubishi, possessing both robustness and agility in addition to the toughness and sheer power expected of a pickup truck. Following in the footsteps of the award for the Xforce last year, I am deeply honored that the all-new Triton has earned such high recognition at the VMARK Vietnam Design Awards this year. This award will provide a boost, but we will also continue doing our utmost to promote the Triton’s appeal to even more customers in Vietnam.”VMARK Vietnam Design Awards 2024 Awards Page (only available in English and Vietnamese) https://www.vietnamdesignweek.org/vmark-vietnam-design-week-2024About Mitsubishi MotorsMitsubishi Motors Corporation (TSE:7211) — a member of the Alliance with Renault and Nissan — is a global automobile company based in Tokyo, Japan, which has about 28,000 employees and a global footprint with production facilities in Japan and the ASEAN region. Mitsubishi Motors has a competitive edge in SUVs, pickup trucks and plug-in hybrid electric vehicles, and appeals to ambitious drivers willing to challenge convention and embrace innovation. Since the production of our first vehicle more than a century ago, Mitsubishi Motors has been a leader in electrification — launched the i-MiEV, the world’s first mass-produced electric vehicle in 2009, followed by the Outlander PHEV, the world’s first plug-in hybrid electric SUV in 2013. With a target of increasing the sales ratio of electrified vehicles to 100% by 2035, Mitsubishi Motors will deliver models that embody Mitsubishi Motors-ness and contribute to the realization of a carbon-neutral society.For more information on Mitsubishi Motors, please visit the company's website athttps://www.mitsubishi-motors.com/en/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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Eisai Presents Data on Benefits of Long-Term Administration of Dual-Acting Lecanemab at the 17th Clinical Trials for Alzheimer’s Disease (CTAD) Conference JCN Newswire

Eisai Presents Data on Benefits of Long-Term Administration of Dual-Acting Lecanemab at the 17th Clinical Trials for Alzheimer’s Disease (CTAD) Conference

TOKYO and CAMBRIDGE, Mass., Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. and Biogen Inc. announced today that the latest findings for lecanemab-irmb (U.S. brand name: LEQEMBI®), an anti-amyloid beta (Aβ) protofibril* antibody for the treatment of early Alzheimer’s disease (AD), were presented at the Clinical Trials for Alzheimer's Disease Conference (CTAD), held in Madrid, Spain, and virtually.Benefits of Continued Treatment with Lecanemab for People with Early ADIn July 2024 at the Alzheimer's Association International Conference (AAIC) 2024, results from the open-label long-term extension study (OLE) following the core study of the lecanemab Phase 3 Clarity AD study were presented, showing that the mean change from baseline in CDR-SB (global cognitive and functional scale) in the lecanemab treated group relative to the placebo group was -0.45 at 18 months, and at 36 months, this expanded to -0.95 compared to a prespecified natural history** cohort of AD. There was a 30% reduction in the relative risk of progressing to the next disease stage In addition, the tau PET substudy of the lecanemab Phase 3 Clarity AD clinical study showed that with three (3) years of continuous treatment with lecanemab, 59% of patients with no or low tau accumulation in the brain (no tau/low tau) at baseline showed improvement or no decline, and 51% showed improvement from baseline on the Clinical Dementia Rating-Sum of Boxes (CDR-SB) global cognitive and functional scale.1Clarity AD data presented at CTAD expand on these initial results to include additional measurements resulting from three (3) years of continuous lecanemab treatment in patients with low levels of amyloid accumulation in the brain at baseline (less than 60 Centiloids: low amyloid). These data show that 46% of patients improved or had no decline, and 33% showed improvement from baseline on the CDR-SB. On the ADAS-Cog14 measurement scale, 46% of patients showed improvement or no decline and 43% showed improvement. On the ADCS MCI-ADL, 51% of patients showed improvement or no decline and 48% showed improvement. These results – from no tau/low tau population and low amyloid populations – suggest that earlier initiation of lecanemab treatment may have a positive impact on disease progression of early AD patients and may provide continued benefits to patients with early AD over the long term.2No new safety findings were observed with continued lecanemab treatment over three (3) years. Most amyloid-related imaging abnormalities (ARIA) occurred in the first six (6) months of treatment. After the first six (6) months, ARIA rates were low and similar to ARIA rates on placebo during the placebo- controlled period. With regards to the incidence of ARIA by ApoEε4 status during the continuous treatment, the incidence was higher in ApoE4 homozygotes than in heterozygotes or non-carriers, but rates of new ARIA were decreased after the completion of the 18 months core study as treatment continued, regardless of ApoEε4 status.2Correlation between Protofibrils and Biomarkers for Neurodegenerative Disease in the AD Brain Dual-acting lecanemab is the only early AD treatment available to support neuronal function by clearing the highly toxic protofibrils that continue to cause neuronal injury and death even after plaques have been cleared from the brain. Protofibrils accumulate early in the AD brain and lead to nerve cell function loss, abnormal nerve processes, inflammation, and memory loss. In non-clinical studies, antibodies against protofibrils prevented protofibril-mediated neuronal dysfunction and memory loss.Accurately quantifying the amount of protofibrils in human cerebrospinal fluid (CSF) has been challenging due to their low concentration. As such, a new measurement method was developed by researchers at Eisai to accurately quantify protofibrils in CSF.Utilizing this new method of measurement, the amount of protofibrils in AD CSF correlated more strongly with neurodegenerative disease biomarkers (CSF total tau and neurogranin) than with CSF Aβ42, a biomarker associated with Aβ plaques accumulation, indicating that protofibrils are closely related to synaptic dysfunction. Furthermore, it was observed that protofibrils, unlike plaques, are diffusible. These results suggest that protofibrils induce synaptic dysfunction, playing an important role in neurodegeneration in AD brains.3Lecanemab Treatment for Early AD: Insights from Long-Term U.S. Clinical StudiesDr. Marwan Noel Sabbagh, Moreno Family Chair for Alzheimer's Research and Vice Chairman for Research and Professor, Department of Neurology, Barrow Neurological Institute, presented outcomes of an analysis of the use of lecanemab treatment between January 6, 2023, and July 30, 2024, based on payment claims data from the Komodo Research Database, a medical database in the U.S. In the U.S., lecanemab is used in accordance with the US FDA-approved indication, dosing, and monitoring guidelines. The analysis found that access to lecanemab treatment is expanding and highlighted opportunities to improve access in rural areas and educational outreach for underserved populations.4Dr. David Watson of the Alzheimer's Research and Treatment Center reported on patients who continued to receive lecanemab treatment following the Phase II Study 201 and Phase III Clarity AD study. A total of 136 patients participated in both studies at this center, and 66 patients chose to continue lecanemab therapy, with 13 patients receiving treatment for more than five (5) years and 40 patients receiving treatment for more than three (3) years. More than half of the patients (15/24) who continued treatment with lecanemab for more than three (3) years after the core phase remained in their initial stage of disease. Further, in a survey of 11 patients (or their caregivers) who received lecanemab treatment for more than five (5) years, all patients responded that they were “very satisfied” or “satisfied” with lecanemab treatment. In addition, between 45% and 73% of patients responded that lecanemab treatment made them feel more positive about their daily life, social activities, memory, etc. "frequently" or "very often."5No new long-term safety findings were observed in these multi-year studies.5Progress in the AHEAD 3-45 Study: Improving Screening Eligibility Using Blood Biomarkers and Completing Patient EnrollmentAHEAD 3-45 is a Phase 3 clinical study for individuals with preclinical AD, meaning they are clinically unimpaired but have intermediate or elevated levels of amyloid in their brains. In the study, blood tests, cognitive function tests (PACC-5***), amyloid PET, MRI, and tau PET were used for screening. Based on the amount of Aβ accumulation in the brain as determined by amyloid PET, subjects were assigned to two (2) trials with different dose settings: the A3 trial, for those with borderline Aβ levels in the brain, and the A45 trial, for those with positive Aβ levels in the brain.6Screening with blood biomarker tests was important to improve eligibility for amyloid PET testing in subjects without cognitive impairment. Using plasma Aβ42/40 ratio and p-tau217/tau217 ratio in theinitial screening reduced screening failure on amyloid PET from more than 70% to less than 30%. In particular, plasma p-tau217 was shown to correlate with amyloid PET, supporting its role as a useful blood biomarker to identify elevated amyloid in the brain.6Enrollment for the AHEAD 3-45 study was completed in October 2024.Lifetime Achievement Award Presented to Professor LannfeltProfessor Emeritus Lars Lannfelt of Uppsala University received the CTAD Lifetime Achievement Award in recognition of his pioneering work in scientific discovery and drug development in AD. As part of this award ceremony, he delivered a keynote speech outlining the discovery of the arctic mutation in familial AD, its application to therapeutic strategies targeting protofibrils for AD treatment, and the development of lecanemab.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with both Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision- making authority.*Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline of this progressive, debilitating condition.7 Protofibrils cause injury to neurons in the brain which, in turn, can negatively impact cognitive function through multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.8**ADNI is a clinical research project launched in 2005 to develop methods to predict the onset of AD and to confirm the effectiveness of treatments. The ADNI observational cohort was pre-specified and used during the design of Clarity AD. The cohort represents the exact population of those in Clarity AD study; matched ADNI participants show similar degree of decline to placebo group out to 18 months.***PACC-5 is a composite measure that provides a highly sensitive measure of changes in cognitive function in individuals with preclinical AD.About lecanemab (LEQEMBI®)Lecanemab is the result of a strategic research alliance between Eisai and BioArctic. It is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). Lecanemab is approved in the U.S., Japan, China, South Korea, Hong Kong, Israel, the United Arab Emirates and Great Britain. Eisai has also submitted applications for approval of lecanemab in 10 countries and regions, including the European Union (EU).LEQEMBI’s approvals in these countries were based on Phase 3 data from Eisai’s, global Clarity AD clinical trial, in which it met its primary endpoint and all key secondary endpoints with statistically significant results. The primary endpoint was the global cognitive and functional scale, Clinical Dementia Rating Sum of Boxes (CDR-SB). In the Clarity AD clinical trial, treatment with lecanemab reduced clinical decline on CDR-SB by 27% at 18 months compared to placebo.9,10 The mean CDR- SB score at baseline was approximately 3.2 in both groups. The adjusted least-squares mean change from baseline at 18 months was 1.21 with lecanemab and 1.66 with placebo (difference, −0.45; 95% confidence interval [CI], −0.67 to −0.23; P
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Eisai Presents Latest Clinical Findings Suggesting Inhibition of Tau Propagation by Anti-MTBR Tau Antibody E2814 at the 17th Clinical Trials on Alzheimer’s Disease Conference (CTAD) JCN Newswire

Eisai Presents Latest Clinical Findings Suggesting Inhibition of Tau Propagation by Anti-MTBR Tau Antibody E2814 at the 17th Clinical Trials on Alzheimer’s Disease Conference (CTAD)

TOKYO, Oct 31, 2024 - (JCN Newswire via SeaPRwire.com) - Eisai Co. Ltd announced today that the latest findings on anti-MTBR (microtubule binding region) tau antibody E2814 were presented at the 17th annual Clinical Trials on Alzheimer’s Disease (CTAD) conference, held in Madrid, Spain, and virtually. Eisai also announced initiation of a Phase II study (Study 202) on E2814 for sporadic early Alzheimer’s Disease (AD).Impact of the anti-MTBR tau antibody E2814 on tau pathology biomarkers in Dominantly Inherited Alzheimer’s Disease (DIAD)E2814 is an investigational anti-MTBR tau antibody designed to target the MTBR of tau. In AD patients, neurofibrillary tangles (NFT) are a pathological hallmark, and they are believed to spread through synaptically connected pathways in the brain, forming the tau propagation hypothesis. It is thought that tau propagation is drivenby the specific tau species containing MTBR, tau seeds that spread tau pathology to different brain regions important for cognition and function.Eisai conducted a Phase I/II clinical study (Study 103, NCT04971733; 7 participants) of the anti-MTBR tau antibody E2814 in patients with Dominantly Inherited Alzheimer’s Disease (DIAD) beginning in June 2021. This study aimed to evaluate the safety and tolerability of E2814 in DIAD patients, with a primary objective of assessing the target engagement of E2814 with MTBR-tau species in their cerebrospinal fluid (CSF). In addition, pharmacodynamicevaluation was performed using multiple biomarkers related to AD tau pathology. In the study, DIAD patients withclinical symptoms were administered E2814 for 12 to 24 months. Data from the Dominantly Inherited Alzheimer Network Observational Study (DIAN-obs), an observational cohort of DIAD, were used as references to evaluate biomarkers changes in E2814 treatment.Compared to the reference data from DIAN-obs, patients who received E2814 showed approximately 75% and 50% reductions of CSF MTBR-tau243 and p-tau217, respectively, reflecting tau pathophysiology. Additionally, braintau accumulation observed by tau PET was stabilized or trended toward decrease in DIAD subjects administered E2814. These results suggest that E2814 inhibited tau propagation and suppressed the accumulation of tau aggregates in brains of people living with DIAD. This will be further investigated in the ongoing Phase II/III Tau NexGen study (NCT05269394) with DIAD patients and the Phase II 202 study (NCT06602258) with sporadic early Alzheimer’s disease (AD) patients.Initiation of Phase II clinical study (Study 202)In September 2024, Eisai initiated a Phase II clinical study (Study 202) for individuals with early AD in the United States. The study is also scheduled to be conducted in Japan in the future. This study is a placebo- controlled,double-blind, parallel-group, dose exploration study, evaluating the safety, tolerability, and biomarker efficacy of E2814 in people living with early AD receiving lecanemab as a backbone anti-Aβ therapy.Eisai positions neurology as a key therapeutic area, and it will continue to create innovation in the development of novel medicines based on cutting-edge neurology research as it seeks to contribute further to improving the benefits of affected individuals and their families in diseases with high unmet needs, such as dementia including AD.This release discusses investigational uses of agents in development and is not intended to convey conclusionsabout efficacy or safety. There is no guarantee that such investigational agents will successfully complete clinical development or gain health authority approval.About E2814An investigational anti-microtubule binding region (MTBR) tau antibody, E2814 is being developed as a disease- modifying agent for tauopathies including sporadic Alzheimer’s disease (AD). Phase I clinical studies are underway. E2814 was discovered as part of the research collaboration between Eisai and University College London. E2814 is designed to prevent the spreading of tau seeds within the brains of affected individuals. In addition, E2814 has been selected as an anti-tautherapy in a Phase II/III Tau NexGen study for the treatment of DIAD, conducted by DIAN-TU led by Washington University School of Medicine in St. Louis, is underway.Biomarkers related to AD tau pathologyAs fluid biomarkers related to AD tau pathology, tau containing the residue 243 (MTBR-tau243) and tau phosphorylated at theresidue 217 (p-tau217) in CSF have been reported.1 In addition, positron emission tomography (tau PET), which specifically detects tau aggregates, is used as an imaging biomarker. These biomarkers are included in the Revised criteria for diagnosis and staging of Alzheimer's disease published by the National Institute on Aging and the Alzheimer's Association (NIA-AA) in June 2024.2(1) Horie K, et al. CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease. Nat Med. 2023. 29. 1954-1963(2) Jack Jr. CR, et al. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. Alzheimers Dement. 2024. 20. 5143-5169For further information: Media Inquiries:Eisai Co., Ltd.Public Relations Department TEL: +81 (0)3-3817-5120Eisai Inc. (U.S.) Libby Holman+1-201-753-1945Libby_Holman@Eisai.comEisai Europe, Ltd. (UK, Europe, Australia, New Zealand and Russia) EMEA Communications Department+44 (0) 786 601 1272EMEA-comms@eisai.net Copyright 2024 JCN Newswire via SeaPRwire.com.
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Mazda Production and Sales Results for September 2024 and for April through September 2024 JCN Newswire

Mazda Production and Sales Results for September 2024 and for April through September 2024

TOKYO, Oct 30, 2024 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation's production and sales results for September 2024 and for April through September 2024 are summarized below.I. Production BreakdownSeptember 2024Apr - Sep 2024Jan - Sep 2024UnitsYoYChange (%)UnitsYoYChange (%)UnitsYoYChange (%)DOMESTIC PRODUCTIONPassenger Vehicles65,047-18.8375,643-5.9558,969-10.2Total65,047-18.8375,643-5.9558,969-10.2 OVERSEAS PRODUCTIONPassenger Vehicles39,244+0.4226,952+17.1335,277+13.1Total39,244+0.4226,952+17.1335,277+13.1 GLOBAL PRODUCTIONPassenger Vehicles104,291-12.5602,595+1.6894,246-2.7Total104,291-12.5602,595+1.6894,246-2.71. Domestic Production(1) September 2024Mazda's domestic production volume in September 2024 decreased 18.8% year on year due to decreased production of passenger vehicles.[Domestic production of key models in September 2024]CX-5:21,133 units(down 40.8% year on year)MAZDA3:10,704 units(up 25.0%)CX-90:7,296 units(down 14.9%)(2) April through September 2024Mazda's domestic production volume in the period from April through September 2024 decreased 5.9% year on year due to decreased production of passenger vehicles.[Domestic production of key models in the period from April through September 2024]CX-5:141,007 units(down 19.8% year on year)MAZDA3:53,009 units(up 6.7%)CX-90:50,331 units(up 42.0%)2. Overseas Production(1) September 2024Mazda's overseas production volume in September 2024 increased 0.4% year on year due to increased production of passenger vehicles.[Overseas production of key models in September 2024]CX-30:11,527 units(down 2.6% year on year)CX-50:9,985 units(up 21.9%)MAZDA3:5,276 units(down 55.5%)(2) April through September 2024Mazda's overseas production volume in the period from April through September 2024 increased 17.1% year on year due to increased production of passenger vehicles.[Overseas production of key models in the period from April through September 2024]CX-30:64,436 units(up 0.2% year on year)CX-50:58,866 units(up 50.1%)MAZDA3:32,646 units(down 21.8%)II. Domestic Sales BreakdownSeptember 2024Apr - Sep 2024Jan - Sep 2024UnitsYoYChange (%)UnitsYoYChange (%)UnitsYoYChange (%)DOMESTIC SALESPassenger Vehicles12,617+14.059,304-21.995,947-26.1Commercial Vehicles923-7.34,850-17.97,674-17.4 Registration Total9,973+14.546,586-27.074,689-33.0Micro-mini Total3,567+6.517,568-2.828,932+4.9Total13,540+12.364,154-21.6103,621-25.5(1) September 2024Mazda's domestic sales volume in September 2024 increased 12.3% year on year due to increased sales of passenger vehicles.Mazda's registered vehicle market share was 3.6% (up 0.4 points year on year), with a 2.2% share of the micro-mini segment (up 0.2 points) and a 3.1% total market share (up 0.3 points).[Domestic sales of key models in September 2024]MAZDA2:2,354 units(up 53.3% year on year)CX-5:2,252 units(up 51.1%)CX-30:1,467 units(up 264.9%)(2) April through September 2024Mazda's domestic sales volume in the period from April through September 2024 decreased 21.6% year on year due to decreased sales of passenger and commercial vehicles.Mazda's registered vehicle market share was 3.3% (down 1.2 points year on year), with a 2.3% share of the micro-mini segment (unchanged year on year) and a 3.0% total market share (down 0.7 points).[Domestic sales of key models in the period from April through September 2024]MAZDA2:12,031 units(up 22.8% year on year)CX-5:9,619 units(down 21.4%)CX-30:6,702 units(down 4.3%)III. Exports BreakdownSeptember 2024Apr - Sep 2024Jan - Sep 2024UnitsYoYChange (%)UnitsYoYChange (%)UnitsYoYChange (%)EXPORTSPassenger Vehicles54,988-15.4334,553-2.1487,949-6.5 North America21,985-6.9151,152+13.0210,401+0.1Europe9,926-38.758,950-36.5107,451-19.2Oceania6,296-3.234,462-3.947,417-7.5Others16,781-10.489,989+13.8122,680-3.9Total54,988-15.4334,553-2.1487,949-6.5(1) September 2024Mazda's export volume in September 2024 decreased 15.4% year on year due to decreased shipments to Europe, North America, Oceania, and other regions.[Exports of key models in September 2024]CX-5:19,047 units(down 38.0% year on year)MAZDA3:9,720 units(up 48.1%)CX-90:8,306 units(up 13.1%)(2) April through September 2024Mazda's export volume in the period from April through September 2024 decreased 2.1% year on year due to decreased shipments to Europe, and Oceania.[Exports of key models in the period from April through September 2024]CX-5:135,974 units(down 16.7% year on year)CX-90:50,103 units(up 45.8%)MAZDA3:49,165 units(up 13.8%)IV. Global Sales BreakdownSeptember 2024Apr - Sep 2024Jan - Sep 2024UnitsYoY Change (%)UnitsYoY Change (%)UnitsYoY Change (%)GLOBAL SALESDomestic Sales13,540+12.364,154-21.6103,621-25.5 U.S.A29,840+6.5213,345+15.8313,449+15.0 China6,425-33.134,424-23.958,139+1.5 Europe17,158-15.288,591-1.3134,540-5.2 Others40,324+8.6229,513+6.6331,359+3.4Overseas Sales93,747-1.3565,873+5.8837,487+5.7Total107,287+0.2630,027+2.2941,108+1.0(1) September 2024Mazda's global sales volume in September 2024 increased 0.2% year on year due to increased sales in the U.S., Japan, and other regions.[Global sales of key models in September 2024]CX-5:29,373 units(up 7.2% year on year)CX-30:18,362 units(down 2.1%)MAZDA3:12,395 units(down 34.1%)(2) April through September 2024Mazda's global sales volume in the period from April through September 2024 increased 2.2% year on year due to increased sales in the U.S., and other regions.[Global sales of key models in the period from April through September 2024]CX-5:176,597 units(up 1.3% year on year)CX-30:113,133 units(up 13.3%)MAZDA3:80,824 units(down 9.7%)(1) Overseas production figures indicate Mazda-brand units coming off the production line (excluding CKD units).(2) Global production figures are the sum total of domestic and overseas production volumes.(3) All information in this press release is as of the date of the publicity. No updates after that date are reflected. Copyright 2024 JCN Newswire via SeaPRwire.com.
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Suzuki and Toyota to Deepen Collaboration in the Field of Electrified Vehicles JCN Newswire

Suzuki and Toyota to Deepen Collaboration in the Field of Electrified Vehicles

Toyota City, Japan, Oct 30, 2024 - (JCN Newswire via SeaPRwire.com) - Suzuki Motor Corporation (Suzuki) and Toyota Motor Corporation (Toyota) have decided to further strengthen collaboration in the supply of a battery EV (BEV) SUV model developed by Suzuki to Toyota. This new model is scheduled to be manufactured at Suzuki Motor Gujarat in India from the spring of 2025.Both Suzuki and Toyota's businesses have their roots in Enshu―the western part of Shizuoka Prefecture―and both companies took on the challenge of switching their businesses from looms to automobiles. Since Suzuki's Chairman (current Senior Advisor) Osamu Suzuki and Toyota's President (current Chairman) Akio Toyoda started exploring business partnerships in 2016, both companies have engaged in a wide-ranging collaboration, aiming to provide people with freedom of movement and fun-to-drive. The fields of collaboration are diverse and include production and mutual supply of vehicles, and the spread of electrified vehicles. As a result, the market launch of collaboration vehicles has expanded to Japan, India, Europe, Africa, and the Middle East.This new development marks the first BEV in the OEM relationship between the two companies. It will be launched worldwide, providing a BEV choice even in the SUV market, which is showing remarkable growth. With this new addition, Suzuki and Toyota will further promote their respective initiatives toward realizing a carbon-neutral society.The new model was designed exclusively as a BEV. A nimble SUV with the sharp driving characteristics of a BEV, it features ample cruising range and a comfortable cabin. It is also available with a 4WD system, offering exceptional drivability on rough roads and a more powerful driving performance.The BEV unit and platform adopted for this model were jointly developed by Suzuki, Toyota, and Daihatsu Motor Co., Ltd., utilizing each company's strength.Comment from Suzuki President Toshihiro Suzuki"Suzuki will supply our first BEV to Toyota globally. I am grateful that the collaboration between the two companies has further deepened in this way. While continuing to be competitors, we will deepen our collaborations toward solving social issues, including the realization of a carbon-neutral society through a multi-pathway approach."Comment from Toyota President Koji Sato"By leveraging the BEV unit and platform that we jointly developed, we will take a new step in our collaboration in the field of electrified vehicles. This will allow us to deliver various choices that contribute to a carbon-neutral society to customers worldwide. We would like to learn from each other's strengths, compete, and further joint efforts based on a multi-pathway approach."About Toyota Motor CorporationToyota Motor Corporation works to develop and manufacture innovative, safe and high-quality products and services that create happiness by providing mobility for all. We believe that true achievement comes from supporting our customers, partners, employees, and the communities in which we operate. Since our founding over 80 years ago in 1937, we have applied our Guiding Principles in pursuit of a safer, greener and more inclusive society. Today, as we transform into a mobility company developing connected, automated, shared and electrified technologies, we also remain true to our Guiding Principles and many of the United Nations' Sustainable Development Goals to help realize an ever-better world, where everyone is free to move.SDGs Initiatives: https://global.toyota/en/sustainability/sdgs/ Copyright 2024 JCN Newswire via SeaPRwire.com.
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Fujitsu and Morinaga Milk Industry jointly develop a simulation system for raw material price fluctuations, speeding up decision-making JCN Newswire

Fujitsu and Morinaga Milk Industry jointly develop a simulation system for raw material price fluctuations, speeding up decision-making

KAWASAKI, Japan, Oct 30, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu and Morinaga Milk Industry Co., Ltd. have jointly developed a system that simulates the impact of raw material price and exchange rate fluctuations on management initiatives and business profits. This system utilizes the Fujitsu Manufacturing Supply Chain Planning offering (1) and is currently in use by Morinaga Milk Industry.Morinaga Milk Industry previously carried out manual data collection among its 23 domestic factories and hundreds of suppliers. This system streamlines the process, enabling early visualization of the impact of raw material price fluctuations, thus contributing to faster decision-making. A two-month trial run with Morinaga Milk Industry carried out previously confirmed improvements in work efficiency and standardization.Fujitsu will continue to support Morinaga Milk Industry's efforts to foster a corporate culture of taking on challenges and contribute to the healthy and happy lives of its customers, viewing this transformation as the essence of Digital Transformation (DX) promotion.OverviewFujitsu Manufacturing Supply Chain Planning is an advanced planning and simulation platform that leverages Fujitsu's deep understanding of industry-specific processes, data, algorithms, business practices, and system architecture cultivated over 30 years.The system provided to Morinaga Milk Industry significantly reduces the time required to grasp and analyze the impact of raw material price fluctuations on profits, enhancing responsiveness to change. Its diverse simulation capabilities will support a shift toward advanced operations, i.e., sales and procurement planning that is adaptable to future expansion, and contribute to cost optimization.Figure 1: Diagram of system provided to Morinaga Milk IndustryFuture PlansWith the launch of integrated budget-sales-supply and demand planning templates on October 1, 2024, Fujitsu plans to expand its offerings to manufacturers who want to be able to respond rapidly to demand fluctuations and inventory optimization.[1]Fujitsu Manufacturing Supply Chain Planning :An offering that realizes a robust and efficient supply chain by supporting rapid decision-making from management to the field and throughout the supply chain through integrated planning that considers supply chain risks. It combines Fujitsu's in-house developed manufacturing scheduler and risk management with Fujitsu's unique templates built on the "Anaplan" platform, the scenario planning and analysis platform designed to optimize decision-making.Fujitsu’s Commitment to the Sustainable Development Goals (SDGs)The Sustainable Development Goals (SDGs) adopted by the United Nations in 2015 represent a set of common goals to be achieved worldwide by 2030.Fujitsu’s purpose — “to make the world more sustainable by building trust in society through innovation” — is a promise to contribute to the vision of a better future empowered by the SDGs.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.
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